Ursofiz
Ursodeoxycholic Acid 150 MG, 300 MG
Ursofiz 150/300 contains ursodeoxycholic Acid that belongs to the group of medicines called
Hepatoprotective agents. it is used to desolve gallstones in various liver-related disorders such as
cirrhosis, sclerosing cholangitis, and liver dyfunction.
Mechanism of action:
- Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver
and protecting liver cells. The main mechanismis anticholelithic. - It is concentrated inbile end decreases biliary cholesterol by:
1. Suppressinghepatic synthesis and secretion of cholesterol
2. Inhibiting its intestinalabsorption - The reduced cholesterol saturation parmits the gradual solubilization of cholesterol from gallstones,
resulting in their eventual dissolution.
Key Features:
- UDCA delays the progression rate of PBC resulting in decreased need for liver transplantation.
- Treatment of PSC patients with high dose UDCA (25-30mg/kg per day) for 1 YEAR lead to
improved biochemistries and the Mayo riske score. - UDCA improve maternal itching scores and liver function tests without
interfering with the fetoplacental estrogen production in patient with
ICP lintrahepatic Cholestasis of Pregnancy)2 - UDCA is well tolersted by pregnant wornen. No fetal or neonatal side-effectsere detected.”
- UDCA hasbeenused in the treatment of gallbladder slone as an alternative to cholecystectomy.
- UDCA is an effective and safe atemative to Vitamin E in non diabetic non cirrhotic Indian NAFLD
patients.
Storage
Store in cool and dry place. Protectes from light and moisture.
Dosage
As Directed By Physician.
